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Sep 24, 2024 · Increased levels of circulating cathepsin D are closely linked with the presence of type 2 diabetes, and cathepsin D might serve as a novel biomarker for cardiac dysfunction in …
Increased mRNA levels for components of the lysosomal, Ca2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients.
4 days ago · Serum cathepsin D levels have been associated with AD dementia and cerebral atrophy, suggesting the potential of cathepsin D as a prognostic biomarker of global cognitive …
In the present study, we found that high plasma levels of cathepsin D, cystatin B and, to a lesser extent, cathepsin L, were associated with increased risk of future CE.
This study is the first to demonstrate an association between elevated pre-arrest CatD levels and in-hospital mortality in IHCA patients.
Cathepsin D is a protein that in humans is encoded by the CTSD gene. [5][6] This gene encodes a lysosomal aspartyl protease composed of a protein dimer of disulfide -linked heavy and light …
Jan 27, 2016 · In this study, we show that high plasma levels of the protease cathepsin D are associated with increased risk for future coronary syndromes. Futhermore, in smokers, cathepsin …
Aug 2, 2025 · While mainly active in acidic conditions, cathepsin D can also exhibit some activity at a neutral pH, and it can be found outside the cell. Cathepsin D is involved in several human …
Previous studies demonstrated that plasma CTSD levels are elevated in NASH patients and that plasma CTSD activity is associated with hepatic insulin resistance in overweight and obese humans.
Mar 24, 2025 · It has been associated with cardiovascular diseases, atherosclerosis, heart failure, and acute conditions such as acute kidney injury (AKI) and pancreatitis [2].
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